Infrastructure

The infrastructure of the research center has been intensively developed in the last years, through the financial support of several national and international research projects of the research group members. Furthermore several instruments were obtained by donations from our long-time collaborators, Terapia Ranbaxy, Farmec, Kynetix.

The infrastructure is organized over several platforms:

  1. Recombinant protein expression and purification Platform – L.6 and L.36
  2. Protein engineering Platform - L.32 and L.33
  3. Enzyme technologies Platform - L.53, L.11, and L.16)
  4. Bioanalytical Platform - L.35 and L.25
  5. Protein crystallization Platform - L.9
  6. Computational facilities

The research center also has access to the strategic research facilities of the Faculty of Chemistry and Chemical Engineering of Babes-Bolyai University (NMR spectrometers. Atomic absorption-emission spectrometer, etc.).

Regulation for the use of biotransformation and biocatalysis research center equipment.

Protein crystallization Platform


Includes facilities for:
Semi-automatized protein crsytallisation, including a Mosquito liquid handler robotic systems, storage systems for microplates, cold room, and visual detection of crystals by microscope. Initial diffraction of the selected crystal can be performed at the vicinal X-ray crystallography facility.

Mosquito Xtal3 - SPT Labtech’s mosquito liquid handler

Manufacturer: SPTLabtech 2020
Mosquito Xtal3 is the protein crystallographer’s favourite liquid handler. It makes protein crystallography screening faster, more cost-effective and quite simply easier than ever before. It brings together speed, accuracy and high precision pipetting of nanoliter volumes with zero cross-contamination from a disposable tip. It has a 3-plate position deck which is the optimal balance between space and functionality.

Technical description

Viaflow liquid handler

Olympus microscope