Scientific papers
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Optimization of reaction parameters for the synthesis of natural aroma esters by factorial design
Dudu Adrian Ioan, Paizs Csaba, Toşa Monica Ioana
Reaction Chemistry and Engineering (2024) 9(11): 2994–3002
DOI: 10.1039/d4re00265b -
The Biocatalytic Potential of Aromatic Ammonia–Lyase from Loktanella atrilutea
Tomoiaga R.B., Ágoston G., Boros K., Nagy L.C., Toşa M.I., Paizs C., Bencze L.C.
ChemBioChem (2024) 25(9): e202400011
DOI: 10.1002/cbic.202400011 -
Transaminase - carbonic anhydrase bi-enzymatic cascade for preparation of (R)-1-arylethan-1-amines and (S)-1-arylethan-1-ols
Barabás L.E., Scrob D.M., Varga A., Kiss L., Toşa M.I., Paizs C.
Reaction Chemistry and Engineering (2023) 8(8): 2001-2010
DOI: 10.1039/d3re00128h -
A robust and efficient lipase based nanobiocatalyst for phenothiazinyl-ethanol resolution
Spelmezan C.-G., Katona G., Bencze L.C., Paizs C., Toşa M.I.
Reaction Chemistry and Engineering (2023) 88(2): 852-862
DOI: 10.1039/d2re00515h -
How to identify and characterize novel transaminases? Two novel transaminases with opposite enantioselectivity for the synthesis of optically active amines
Gal C.A., Barabás L.-E., Varga A., Csuka P., Bencze L.C., Toşa M.I., Poppe L., Paizs C.
Molecular Catalysis (2022) 531: 112660
DOI: 10.1016/j.mcat.2022.112660 -
Cross-Linked Enzyme-Adhered Nanoparticles (CLEANs) for Continuous-Flow Bioproduction
Nagy F., Sánta-Bell E., Jipa M., Hornyánszky G., Szilágyi A., László K., Katona G., Paizs C., Poppe L., Balogh-Weiser D.
ChemSusChem (2022) 15(2): e202102284
DOI: 10.1002/cssc.202102284 -
Deep eutectic solvents-a new additive in the encapsulation of lipase B from: Candida antarctica: Biocatalytic applications
Dudu A.I., Bencze L.C., Paizs C., Toşa M.I.
Reaction Chemistry and Engineering (2022) 7(2): 442-449
DOI: 10.1039/d1re00469g -
Recent Progress in the Selective Fluorinations of Some Functionalized Cycloalkenes
Nonn M., Paizs C., Kiss L.
Chemical Record (2022) 22(9): e202200130
DOI: 10.1002/tcr.202200130 -
Cross-Linked Enzyme-Adhered Nanoparticles (CLEANs) for Continuous-Flow Bioproduction
Nagy F., Sánta-Bell E., Jipa M., Hornyánszky G., Szilágyi A., László K., Katona G., Paizs C., Poppe L., Balogh-Weiser D.
ChemSusChem (2022) 15(2): e202102284
DOI: 10.1002/cssc.202102284 -
Lipase on carbon nanotubes-an active, selective, stable and easy-to-optimize nanobiocatalyst for kinetic resolutions
Gal C.A., Barabás L.E., Bartha Vári J.-H., Moisă M.E., Balogh-Weiser D., Bencze L.C., Poppe L., Paizs C., Toşa M.I.
Reaction Chemistry and Engineering (2021) 6(12): 2391-2399
DOI: 10.1039/d1re00342a -
Characterization of yeast strains with ketoreductase activity for bioreduction of ketones
Csuka P., Nagy-Győr L., Molnár Z., Paizs C., Bódai V., Poppe L.
Periodica Polytechnica Chemical Engineering (2021) 65(3): 299-307
DOI: 10.3311/PPch.17429 -
Robust, site-specifically immobilized phenylalanine ammonia-lyases for the enantioselective ammonia addition of cinnamic acids
Boros K., Moisă M.E., Nagy C.L., Paizs C., Toşa M.I., Bencze L.C.
Catalysis Science and Technology (2021) 11(16): 5553-5563
DOI: 10.1039/d1cy00195g -
Green Process for the Enzymatic Synthesis of Aroma Compounds Mediated by Lipases Entrapped in Tailored Sol-Gel Matrices
Dudu A.I., Lacatus M.A., Bencze L.C., Paizs C., Toşa M.I.
ACS Sustainable Chemistry and Engineering (2021) 9(15): 5461-5469
DOI: 10.1021/acssuschemeng.1c00965 -
Substrate Tunnel Engineering Aided by X-ray Crystallography and Functional Dynamics Swaps the Function of MIO-Enzymes
Bata Z., Molnár Z., Madaras E., Molnár B., Sánta-Bell E., Varga A., Leveles I., Qian R., Hammerschmidt F., Paizs C., Vértessy B.G., Poppe L.
ACS Catalysis (2021) 11(8): 4538-4549
DOI: 10.1021/acscatal.1c00266 -
A novel phenylalanine ammonia-lyase from Pseudozyma antarctica for stereoselective biotransformations of unnatural amino acids
Varga A., Csuka P., Sonesouphap O., Bánóczi G., Toşa M.I., Katona G., Molnár Z., Bencze L.C., Poppe L., Paizs C.
Catalysis Today (2021) 366: 185-194
DOI: 10.1016/j.cattod.2020.04.002 -
Oscillations and collective behavior in convective flows
Gergely A., Paizs C., Tötös R., Néda Z.
Physics of Fluids (2021) 33(12): 124104
DOI: 10.1063/5.0073347 -
Flickering candle flames and their collective behavior
Gergely A., Sándor B., Paizs C., Tötös R., Néda Z.
Scientific Reports (2020) 10(1): 21305
DOI: 10.1038/s41598-020-78229-x -
Magnetic nanoparticles with dual surface functions—efficient carriers for metalloporphyrin-catalyzed drug metabolite synthesis in batch and continuous-flow reactors
Balogh-Weiser D., Decsi B., Krammer R., Dargó G., Ender F., Mizsei J., Berkecz R., Gyarmati B., Szilágyi A., Tőtős R., Paizs C., Poppe L., Balogh G.T.
Nanomaterials (2020) 10(12): 2329
DOI: 10.3390/nano10122329 -
Solvent-Free Biocatalytic Synthesis of 2,5-bis-(Hydroxymethyl)Furan Fatty Acid Diesters from Renewable Resources
Lăcătuş M.A., Dudu A.I., Bencze L.C., Katona G., Irimie F.-D., Paizs C., Toşa M.I.
ACS Sustainable Chemistry and Engineering (2020) 8(3): 1611-1617
DOI: 10.1021/acssuschemeng.9b06442 -
Fluorescent enzyme-coupled activity assay for phenylalanine ammonia-lyases
Moisă M.E., Amariei D.A., Nagy E.Z.A., Szarvas N., Toşa M.I., Paizs C., Bencze L.C.
Scientific Reports (2020) 10(1): 18418
DOI: 10.1038/s41598-020-75474-y -
Efficient biodiesel production catalyzed by nanobioconjugate of lipase from pseudomonas fluorescens
Bartha-Vári J.-H., Moisă M.E., Bencze L.C., Irimie F.-D., Paizs C., Toşa M.I.
Molecules (2020) 25(3): 651
DOI: 10.3390/molecules25030651 -
Conservation of the biocatalytic activity of whole yeast cells by supported sol – gel entrapment for efficient acyloin condensation
Nagy-Győr L., Farkas E., Lăcătuș M., Tóth G., Incze D., Hornyánszky G., Bódai V., Paizs C., Poppe L., Balogh-Weiser D.
Periodica Polytechnica Chemical Engineering (2020) 64(2): 153-161
DOI: 10.3311/PPch.14645 -
Effcient and stable magnetic chitosan-lipase B from candida antarctica bioconjugates in the enzymatic kinetic resolution of racemic heteroarylethanols
Spelmezan C.G., Bencze L.C., Katona G., Irimie F.D., Paizs C., Toşa M.I.
Molecules (2020) 25(2): 350
DOI: 10.3390/molecules25020350 -
Mapping the Hydrophobic Substrate Binding Site of Phenylalanine Ammonia-Lyase from Petroselinum crispum
Nagy E.Z.A., Tork S.D., Lang P.A., Filip A., Irimie F.D., Poppe L., Toşa M.I., Schofield C.J., Brem J., Paizs C., Bencze L.C.
ACS Catalysis (2019) 9(9): 8825-8834
DOI: 10.1021/acscatal.9b02108 -
The production of L- and D-phenylalanines using engineered phenylalanine ammonia lyases from Petroselinum crispum
Tork S.D., Nagy E.Z.A., Cserepes L., Bordea D.M., Nagy B., Toşa M.I., Paizs C., Bencze L.C.
Scientific Reports (2019) 9(1): 20123
DOI: 10.1038/s41598-019-56554-0 -
How to Turn Yeast Cells into a Sustainable and Switchable Biocatalyst? On-Demand Catalysis of Ketone Bioreduction or Acyloin Condensation
Nagy-Györ L., Lăcătuş M., Balogh-Weiser D., Csuka P., Bódai V., Erdélyi B., Molnár Z., Hornyánszky G., Paizs C., Poppe L.
ACS Sustainable Chemistry and Engineering (2019) 7(24): 19375-19383
DOI: 10.1021/acssuschemeng.9b03367 -
Liver-on-a-chip-magnetic nanoparticle bound synthetic metalloporphyrin-catalyzed biomimetic oxidation of a drug in a magnechip reactor
Decsi B., Krammer R., Hegedus K., Ender F., Gyarmati B., Szilágyi A., Totos R., Katona G., Paizs C., Balogh G.T., Poppe L., Balogh-Weiser D.
Micromachines (2019) 10(10): 668
DOI: 10.3390/mi10100668 -
Immobilized whole-cell transaminase biocatalysts for continuous-flow kinetic resolution of amines
Molnár Z., Farkas E., Lakó Á., Erdélyi B., Kroutil W., Vértessy B.G., Paizs C., Poppe L.
Catalysts (2019) 9(5): 438
DOI: 10.3390/catal9050438 -
"Fishing and hunting"-selective immobilization of a recombinant phenylalanine ammonia-lyase from fermentation media
Sánta-Bell E., Molnár Z., Varga A., Nagy F., Hornyánszky G., Paizs C., Balogh-Weiser D., Poppe L.
Molecules (2019) 24(22): 4146
DOI: 10.3390/molecules24224146 -
Exploring the substrate scope of ferulic acid decarboxylase (FDC1) from Saccharomyces cerevisiae
Nagy E.Z.A., Nagy C.L., Filip A., Nagy K., Gál E., Tőtős R., Poppe L., Paizs C., Bencze L.C.
Scientific reports (2019) 9(1): 647
DOI: 10.1038/s41598-018-36977-x -
“Geländer” macrocycles: Synthesis, chirality and racemisation barriers
Lar C., Moisӑ M.E., Bogdan E., Terec A., Hӑdade N.D., Grosu I., David L., Paizs C., Grosu I.G.
Tetrahedron Letters (2019) 60(4): 335-340
DOI: 10.1016/j.tetlet.2018.12.047 -
Continuous-flow enzymatic kinetic resolution mediated by a lipase nanobioconjugate
Moisă M.E., Bencze L.C., Paizs C., Toşa M.I.
Studia Universitatis Babes-Bolyai Chemia (2019) 64(2Tom1): 79-86
DOI: 10.24193/subbchem.2019.2.07 -
Click reaction-aided enzymatic kinetic resolution of secondary alcohols
Moisă M.E., Poppe L., Gal C.A., Bencze L.C., Irimie F.D., Paizs C., Peter F., Toşa M.I.
Reaction Chemistry and Engineering (2018) 3(5): 790-798
DOI: 10.1039/c8re00091c -
Tailored Mutants of Phenylalanine Ammonia-Lyase from Petroselinum crispum for the Synthesis of Bulky l- and d-Arylalanines
Filip A., Nagy E.Z.A., Tork S.D., Bánóczi G., Toşa M.I., Irimie F.D., Poppe L., Paizs C., Bencze L.C.
ChemCatChem (2018) 10(12): 2627-2633
DOI: 10.1002/cctc.201800258 -
Eco-Friendly Enzymatic Production of 2,5-Bis(hydroxymethyl)furan Fatty Acid Diesters, Potential Biodiesel Additives
Lăcătuş M.A., Bencze L.C., Toşa M.I., Paizs C., Irimie F.-D.
ACS Sustainable Chemistry and Engineering (2018) 6(9): 11353-11359
DOI: 10.1021/acssuschemeng.8b01206 -
Chemoenzymatic Dynamic Kinetic Resolution of Amines in Fully Continuous-Flow Mode
Farkas E., Oláh M., Földi A., Kóti J., Éles J., Nagy J., Gal C.A., Paizs C., Hornyánszky G., Poppe L.
Organic Letters (2018) 20(24): 8052-8056
DOI: 10.1021/acs.orglett.8b03676 -
Co-immobilized Whole Cells with ω-Transaminase and Ketoreductase Activities for Continuous-Flow Cascade Reactions
Nagy-Győr L., Abaházi E., Bódai V., Sátorhelyi P., Erdélyi B., Balogh-Weiser D., Paizs C., Hornyánszky G., Poppe L.
ChemBioChem (2018) 19(17): 1845-1848
DOI: 10.1002/cbic.201800286 -
Covalently immobilized Trp60Cys mutant of Ω-transaminase from Chromobacterium violaceum for kinetic resolution of racemic amines in batch and continuous-flow modes
Abaházi E., Sátorhelyi P., Erdélyi B., Vértessy B.G., Land H., Paizs C., Berglund P., Poppe L.
Biochemical Engineering Journal (2018) 132(27): 270-278
DOI: 10.1016/j.bej.2018.01.022 -
Pseudomonas fluorescens Strain R124 Encodes Three Different MIO Enzymes
Csuka P., Juhász V., Kohári S., Filip A., Varga A., Sátorhelyi P., Bencze L.C., Barton H., Paizs C., Poppe L.
ChemBioChem (2018) 19(4): 411-418
DOI: 10.1002/cbic.201700530 -
Expanding the substrate scope of phenylalanine ammonia-lyase from: Petroselinum crispum towards styrylalanines
Bencze L.C., Filip A., Bánóczi G., Toşa M.I., Irimie F.D., Gellért Á., Poppe L., Paizs C.
Organic and Biomolecular Chemistry (2017) 15(17): 3717-3727
DOI: 10.1039/c7ob00562h -
Tailored sol-gel immobilized lipase preparates for the enzymatic kinetic resolution of heteroaromatic alcohols in batch and continuous flow systems
Moisă M.E., Spelmezan C.G., Paul C., Bartha-Vári J.H., Bencze L.C., Irimie F.D., Paizs C., Péter F., Toşa M.I.
RSC Advances (2017) 7(83): 52977-52987
DOI: 10.1039/c7ra10157k -
A Methylidene Group in the Phosphonic Acid Analogue of Phenylalanine Reverses the Enantiopreference of Binding to Phenylalanine Ammonia-Lyases
Bata Z., Qian R., Roller A., Horak J., Bencze L.C., Paizs C., Hammerschmidt F., Vértessy B.G., Poppe L.
Advanced Synthesis and Catalysis (2017) 359(12): 2109-2120
DOI: 10.1002/adsc.201700428 -
Covalently Immobilized Lipases are Efficient Stereoselective Catalysts for the Kinetic Resolution of rac-(5-Phenylfuran-2-yl)-β-alanine Ethyl Ester Hydrochlorides
Nagy B., Galla Z., Bencze L.C., Toşa M.I., Paizs C., Forró E., Fülöp F.
European Journal of Organic Chemistry (2017) 2017(20): 2878-2882
DOI: 10.1002/ejoc.201700174 -
Aminated single-walled carbon nanotubes as carrier for covalent immobilization of phenylalanine ammonia-lyase
Bartha-Vári J.H., Bencze L.C., Bell E., Poppe L., Katona G., Irimie F.-D., Paizs C., Toşa M.I.
Periodica Polytechnica Chemical Engineering (2017) 61(1): 59-66
DOI: 10.3311/PPch.10417 -
Validated LC-MS/MS method for the concomitant determination of amoxicillin and clavulanic acid from human plasma
Balázsi J., Paizs C., Irimie F.-D., Toşa M.I., Bencze L.C., Tőtős R.
Studia Universitatis Babes-Bolyai Chemia (2017) 62(2Tom1): 167-178
DOI: 10.24193/subbchem.2017.2.12 -
Nanobioconjugates of Candida antarctica lipase B and single-walled carbon nanotubes in biodiesel production
Bencze L.C., Bartha-Vári J.H., Katona G., Toşa M.I., Paizs C., Irimie F.-D.
Bioresource Technology (2016) 200(2): 853-860
DOI: 10.1016/j.biortech.2015.10.072 -
Influence of the aromatic moiety in α- And β-arylalanines on their biotransformation with phenylalanine 2,3-aminomutase from: Pantoea agglomerans
Varga A., Bánóczi G., Nagy B., Bencze L.C., Toşa M.I., Gellért Á., Irimie F.D., Rétey J., Poppe L., Paizs C.
RSC Advances (2016) 6(61): 56412-56420
DOI: 10.1039/c6ra02964g -
Wickerhamomyces subpelliculosus as whole-cell biocatalyst for stereoselective bioreduction of ketones
Bódai V., Nagy-Győr L., Örkényi R., Molnár Z., Kohári S., Erdélyi B., Nagymáté Z., Romsics C., Paizs C., Poppe L., Hornyánszky G.
Journal of Molecular Catalysis B: Enzymatic (2016) 134: 206-214
DOI: 10.1016/j.molcatb.2016.11.003 -
Microfluidic multiple cell chip reactor filled with enzyme-coated magnetic nanoparticles - An efficient and flexible novel tool for enzyme catalyzed biotransformations
Ender F., Weiser D., Nagy B., Bencze C.L., Paizs C., Pálovics P., Poppe L.
Journal of Flow Chemistry (2016) 6(1): 43-52
DOI: 10.1556/1846.2015.00036 -
Heterocycles 36. Single-walled carbon nanotubes-bound n,n-diethyl ethanolamine as mild and efficient racemisation agent in the enzymatic DKR of 2-Arylthiazol-4-yl-alanines
Leonte D., Bencze L.C., Paizs C., Toşa M.I., Zaharia V., Dan Irimie F.
Molecules (2016) 21(1): 25
DOI: 10.3390/molecules21010025 -
Expression and purification of recombinant phenylalanine 2,3-aminomutase from Pantoea agglomerans
Varga A., Filip A., Bencze L.-C., Sátorhelyi P., Bell E., Vértessy B.G., Poppe L., Paizs C.
Studia Universitatis Babes-Bolyai Chemia (2016) 61(2): 7-19 -
Expression and purification of recombinant phenylalanine ammonia-lyase from Petroselinum crispum
Dima N.A., Filip A., Bencze L.C., Oláh M., Sátorhelyi P., Vértessy B.G., Poppe L., Paizs C.
Studia Universitatis Babes-Bolyai Chemia (2016) 61(2): 21-34 -
Albumin adsorption study onto hydroxyapatite-multiwall carbon nanotube based composites
Czikó M., Bogya E.S., Paizs C., Katona G., Konya Z., Kukovecz Á., Barabás R.
Materials Chemistry and Physics (2016) 180(83): 314-325
DOI: 10.1016/j.matchemphys.2016.06.012 -
Phenylalanine Ammonia-Lyase-Catalyzed Deamination of an Acyclic Amino Acid: Enzyme Mechanistic Studies Aided by a Novel Microreactor Filled with Magnetic Nanoparticles
Weiser D., Bencze L.C., Bánóczi G., Ender F., Kiss R., Kõkai E., Szilágyi A., Vértessy B.G., Farkas Ö., Paizs C., Poppe L.
ChemBioChem (2015) 16(16): 2283-2288
DOI: 10.1002/cbic.201500444 -
Immobilization of Phenylalanine Ammonia-Lyase on Single-Walled Carbon Nanotubes for Stereoselective Biotransformations in Batch and Continuous-Flow Modes
Bartha-Vári J.H., Toşa M.I., Irimie F.-D., Weiser D., Boros Z., Vértessy B.G., Paizs C., Poppe L.
ChemCatChem (2015) 7(7): 1122-1128
DOI: 10.1002/cctc.201402894 -
Synthesis of enantiopure l-(5-phenylfuran-2-yl)alanines by a sequential multienzyme process
Bencze L.C., Komjáti B., Pop L.-A., Paizs C., Irimie F.-D., Nagy J., Poppe L., Toşa M.I.
Tetrahedron Asymmetry (2015) 26(18-19): 59353
DOI: 10.1016/j.tetasy.2015.08.004 -
Heterocycles 38. Biocatalytic synthesis of new heterocyclic mannich bases and derivatives
Leonte D., Bencze L.C., Paizs C., Irimie F.D., Zaharia V.
Molecules (2015) 20(7): 12300-12313
DOI: 10.3390/molecules200712300 -
New chemo-enzymatic approaches for the synthesis of (R)- and (S)-bufuralol
Nagy B., Dima N., Paizs C., Brem J., Irimie F.D., Toşa M.I.
Tetrahedron Asymmetry (2014) 25(18-19): 1316-1322
DOI: 10.1016/j.tetasy.2014.08.002 -
Expression and properties of the highly alkalophilic phenylalanine ammonia-lyase of thermophilic Rubrobacter xylanophilus
Kovaćs K., Bańóczi G., Varga A., Szabó I., Holczinger A., Hornyánszky G., Zagyva I., Paizs C., V́ertessy B.G., Poppe L.
PLoS ONE (2014) 9(1): e85943
DOI: 10.1371/journal.pone.0085943 -
Bisepoxide cross-linked enzyme aggregates - New immobilized biocatalysts for selective biotransformations
Weiser D., Varga A., Kovács K., Nagy F., Szilágyi A., Vértessy B.G., Paizs C., Poppe L.
ChemCatChem (2014) 6(5): 1463-1469
DOI: 10.1002/cctc.201300806 -
Surface modification of silica gels for selective adsorption of bacterial lipases
Boros Z., Abaháziová E., Weiser D., Kovács P., Paizs C., Poppe L.
Studia Universitatis Babes-Bolyai Chemia (2014) 59(4): 33-38
DOI: 10.1002/ep.11897 -
The Interaction of Nitrophenylalanines with Wild Type and Mutant 4-Methylideneimidazole-5-one-less Phenylalanine Ammonia Lyase
Toşa M.I., Brem J., Mantu A., Irimie F.D., Paizs C., Rétey J.
ChemCatChem (2013) 5(3): 779-783
DOI: 10.1002/cctc.201200536 -
Lipase-catalyzed asymmetric acylation in the chemoenzymatic synthesis of furan-based alcohols
Hara P., Turcu M.-C., Sundell R., Toşa M., Paizs C., Irimie F.-D., Kanerva L.T.
Tetrahedron Asymmetry (2013) 24(2-3): 142-150
DOI: 10.1016/j.tetasy.2012.11.016 -
Sequential enzymatic procedure for the preparation of enantiomerically pure 2-heteroaryl-2-hydroxyacetic acids
Naghi M.A., Bencze L.C., Brem J., Paizs C., Irimie F.D., Toşa M.I.
Tetrahedron Asymmetry (2012) 23(2): 181-187
DOI: 10.1016/j.tetasy.2012.01.019 -
Immobilization to improve the properties of Pseudomonas fluorescens lipase for the kinetic resolution of 3-aryl-3-hydroxy esters
Brem J., Turcu M.C., Paizs C., Lundell K., Toşa M.-I., Irimie F.-D., Kanerva L.T.
Process Biochemistry (2012) 47(1): 119-126
DOI: 10.1016/j.procbio.2011.10.020 -
Chemoenzymatic preparation of 1-heteroarylethanamines of low solubility
Brem J., Bencze L.-C., Liljeblad A., Turcu M.C., Paizs C., Irimie F.-D., Kanerva L.T.
European Journal of Organic Chemistry (2012) 11(17): 3288-3294
DOI: 10.1002/ejoc.201200330 -
Biodiesel production using enzymatic transesterification - Current state and perspectives
Gog A., Roman M., Toşa M., Paizs C., Irimie F.D.
Renewable Energy (2012) 39(1): 10-16
DOI: 10.1016/j.renene.2011.08.007 -
Preparation of unnatural amino acids with ammonia-lyases and 2,3-aminomutases
Poppe L., Paizs C., Kovács K., Irimie F.-D., Vértessy B.
Methods in Molecular Biology (2012) 794(3): 3-19
DOI: 10.1007/978-1-61779-331-8_1 -
Chemoenzymatic one-pot synthesis of both (R)- and (S)-aryl-1,2-ethanediols
Bencze L.C., Paizs C., Toşa M.I., Irimie F.D., Rétey J.
ChemCatChem (2011) 3(2): 343-346
DOI: 10.1002/cctc.201000295 -
Lipase mediated sequential resolution of aromatic β-hydroxy esters using fatty acid derivatives
Brem J., Naghi M., Toşa M.-I., Boros Z., Poppe L., Irimie F.-D., Paizs C.
Tetrahedron Asymmetry (2011) 22(16-17): 1672-1679
DOI: 10.1016/j.tetasy.2011.09.005 -
Lipase-catalyzed kinetic resolutions of racemic 1-(10-ethyl-10H- phenothiazin-1,2, and 4-yl)ethanols and their acetates
Brem J., Pilbák S., Paizs C., Bánóczi G., Irimie F.-D., Toşa M.-I., Poppe L.
Tetrahedron Asymmetry (2011) 22(8): 916-923
DOI: 10.1016/j.tetasy.2011.05.009 -
Sequential use of regio- and stereoselective lipases for the efficient kinetic resolution of racemic 1-(5-phenylfuran-2-yl)ethane-1,2-diols
Bencze L.C., Paizs C., Toşa M.I., Irimie F.D.
Tetrahedron Asymmetry (2011) 22(6): 675-683
DOI: 10.1016/j.tetasy.2011.03.006 -
Lipases A and B from Candida antarctica in the enantioselective acylation of ethyl 3-heteroaryl-3-hydroxypropanoates: Aspects on the preparation and enantiopreference
Brem J., Liljeblad A., Paizs C., Toşa M.I., Irimie F.-D., Kanerva L.T.
Tetrahedron Asymmetry (2011) 22(3): 315-322
DOI: 10.1016/j.tetasy.2011.01.027 -
Lipase-catalyzed synthesis of both enantiomers of 3-chloro-1-arylpropan-1- ols
Pop L.A., Czompa A., Paizs C., Toa M.I., Vass E., Mátyus P., Irimie F.-D.
Synthesis (2011) 22(18): T49711SS
DOI: 10.1055/s-0030-1260149 -
CaL-B a highly selective biocatalyst for the kinetic resolution of furylbenzthiazole-2-yl-ethanols and acetates
Bencze L.C., Paizs C., Toşa M.I., Trif M., Irimie F.D.
Tetrahedron Asymmetry (2010) 21(16): 1999-2004
DOI: 10.1016/j.tetasy.2010.06.010 -
Lipase-catalyzed kinetic resolution of racemic 1-(10-alkyl-10H- phenothiazin-3-yl)ethanols and their butanoates
Brem J., Toşa M.-I., Paizs C., Munceanu A., Matković-Čalogović D., Irimie F.-D.
Tetrahedron Asymmetry (2010) 21(16): 1993-1998
DOI: 10.1016/j.tetasy.2010.06.007 -
Synthesis of enantiomerically enriched (R)- and (S)-benzofuranyl- and benzo[b]thiophenyl-1,2-ethanediols via enantiopure cyanohydrins as intermediates
Bencze L.C., Paizs C., Toşa M.I., Vass E., Irimie F.D.
Tetrahedron Asymmetry (2010) 21(4): 443-450
DOI: 10.1016/j.tetasy.2010.01.018 -
Substituent effects on the stereochemical outcome of the baker's yeast-mediated biotransformation of α-hydroxy- and α-acetoxymethyl-5-phenylfuran-2-yl-ethanones
Bencze L.C., Paizs C., Toşa M.I., Irimie F.D.
Tetrahedron Asymmetry (2010) 21(3): 356-364
DOI: 10.1016/j.tetasy.2010.02.004 -
Enzyme-catalyzed synthesis of (R)- and (S)-3-hydroxy-3-(10-alkyl-10H-phenothiazin-3-yl)propanoic acids
Brem J., Toşa M.I., Paizs C., Vass E., Irimie F.D.
Tetrahedron Asymmetry (2010) 21(3): 365-373
DOI: 10.1016/j.tetasy.2010.02.006 -
2-amino-3-(5-phenylfuran-2-yl)propionic acids and 5-phenylfuran-2-ylacrylic acids are novel substrates of phenylalanine ammonia-lyase
Paizs C., Toşa M.I., Bencze L.C., Brem J., Irimie F.D., Rétey J.
Heterocycles (2010) 82(2): 1217-1228
DOI: 10.3987/COM-10-S(E)60 -
New ways for old structures
Irimie F.D., Paizs C., Toşa M., Podea P.
Studia Universitatis Babes-Bolyai Chemia (2009) 4(1): 7-16 -
The effect of electromagnetic fields on baker's yeast population dynamics, biocatalytic activity and selectivity
Sandu D., Lingvay I., Lányi S., Micu D.D., Popescu C.L., Brem J., Bencze L.C., Paizs C.
Studia Universitatis Babes-Bolyai Chemia (2009) 4(2): 195-201 -
Enzyme-catalyzed synthesis of (R)- and (S)-3-heteroaryl-3-hydroxy-propanoic acids and their derivatives
Brem J., Paizs C., Toşa M.I., Vass E., Irimie F.D.
Tetrahedron Asymmetry (2009) 20(4): 489-496
DOI: 10.1016/j.tetasy.2009.02.001 -
The putative coenzyme B
12 -dependent methylmalonyl-CoA mutase from potatoes is a phosphatasePaizs C., Diemer T., Rétey J.
Bioorganic Chemistry (2008) 36(6): 261-264
DOI: 10.1016/j.bioorg.2008.06.002 -
Chemoenzymatic synthesis of (R)- and (S)-1-heteroarylethanols
Toşa M.I., Podea P.V., Paizs C., Irimie F.D.
Tetrahedron Asymmetry (2008) 19(17): 2068-2071
DOI: 10.1016/j.tetasy.2008.08.023 -
Baker's yeast-mediated synthesis of (R)- and (S)-heteroaryl-ethane-1,2-diols
Podea P.V., Paizs C., Toşa M.I., Irimie F.D.
Tetrahedron Asymmetry (2008) 19(16): 1959-1964
DOI: 10.1016/j.tetasy.2008.07.030 -
Lipase-catalyzed kinetic resolution of racemic 1-heteroarylethanols-experimental and QM/MM study
Toşa M., Pilbák S., Moldovan P., Paizs C., Szatzker G., Szakács G., Novák L., Irimie F.-D., Poppe L.
Tetrahedron Asymmetry (2008) 19(15): 1844-1852
DOI: 10.1016/j.tetasy.2008.07.004 -
Chemoenzymatic preparation of enantiopure l-benzofuranyl- and l-benzo[b]thiophenyl alanines
Podea P.V., Toşa M.I., Paizs C., Irimie F.D.
Tetrahedron Asymmetry (2008) 19(4): 500-511
DOI: 10.1016/j.tetasy.2008.01.031 -
Investigation of the mechanism of action of pyrogallol-phloroglucinol transhydroxylase by using putative intermediates
Paizs C., Bartlewski-Hof U., Rétey J.
Chemistry - A European Journal (2007) 13(10): 2805-2811
DOI: 10.1002/chem.200601053 -
Inhibition of histidine ammonia lyase by heteroaryl-alanines and acrylates
Katona A., Toşa M.I., Paizs C., Rétey J.
Chemistry and Biodiversity (2006) 3(5): 502-508
DOI: 10.1002/cbdv.200690053 -
The interaction of heteroaryl-acrylates and alanines with phenylalanine ammonia-lyase from parsley
Paizs C., Katona A., Rétey J.
Chemistry - A European Journal (2006) 12(10): 2739-2744
DOI: 10.1002/chem.200501034 -
Chemoenzymatic one-pot synthesis of enantiopure L-arylalanines from arylaldehydes
Paizs C., Katona A., Rétey J.
European Journal of Organic Chemistry (2006) 12(5): 1113-1116
DOI: 10.1002/ejoc.200500902 -
NIR surface enhanced Raman spectroscopy and bands assignment by DFT calculations of non-natural β-amino acids
Iliescu T., Maniu D., Chis V., Irimie F.D., Paizs Cs., Toşa M.
Chemical Physics (2005) 310(1-3): 189-199
DOI: 10.1016/j.chemphys.2004.10.034 -
Biocatalytic enantioselective preparation of phenothiazine-based cyanohydrin acetates: Kinetic and dynamic kinetic resolution
Paizs C., Tähtinen P., Toşa M., Majdik C., Irimie F.-D., Kanerva L.T.
Tetrahedron (2004) 60(46 SPEC. ISS.): 10533-10540
DOI: 10.1016/j.tet.2004.06.136 -
Kinetic resolution of 1-(benzofuran-2-yl)ethanols by lipase-catalyzed enantiomer selective reactions
Paizs C., Toşa M., Bódai V., Szakács G., Kmecz I., Simándi B., Majdik C., Novák L., Irimie F.-D., Poppe L.
Tetrahedron Asymmetry (2003) 14(13): 1943-1949
DOI: 10.1016/S0957-4166(03)00358-6 -
Preparation of novel phenylfuran-based cyanohydrin esters: Lipase-catalysed kinetic and dynamic resolution
Paizs C., Tähtinen P., Lundell K., Poppe L., Irimie F.-D., Kanerva L.T.
Tetrahedron Asymmetry (2003) 14(13): 1895-1904
DOI: 10.1016/S0957-4166(03)00286-6 -
Optically active 1-(benzofuran-2-yl)ethanols and ethane-1,2-diols by enantiotopic selective bioreductions
Paizs C., Toşa M., Majdik C., Moldovan P., Novák L., Kolonits P., Marcovici A., Irimie F.-D., Poppe L.
Tetrahedron Asymmetry (2003) 14(11): 1495-1501
DOI: 10.1016/S0957-4166(03)00222-2 -
Raman, infrared, and surface-enhanced Raman spectroscopy in combination with ab initio and density functional theory calculations on 10-isopropyl-10H-phenothiazine-5-oxide
Bolboaca M., Iliescu T., Paizs Cs., Irimie F.D., Kiefer W.
Journal of Physical Chemistry A (2003) 107(11): 1811-1818
DOI: 10.1021/jp021731j -
Candida antarctica lipase A in the dynamic resolution of novel furylbenzotiazol-based cyanohydrin acetates
Paizs C., Toşa M., Majdik C., Tähtinen P., Irimie F.D., Kanerva L.T.
Tetrahedron Asymmetry (2003) 14(5): 619-627
DOI: 10.1016/S0957-4166(03)00025-9 -
Baker's yeast mediated preparation of (10-alkyl-10H-phenothiazin-3-yl)methanols
Toşa M., Paizs C., Majdik C., Moldovan P., Novák L., Kolonits P., Szabó É., Poppe L., Irimie F.-D.
Journal of Molecular Catalysis - B Enzymatic (2002) 17(6): 241-248
DOI: 10.1016/S1381-1177(02)00015-2 -
Separation of N-alkyl phenothiazine sulfones by HPTLC using an optimum mobile phase
Cimpoiu C., Hodisan S., Toa M., Paizs C., Majdik C., Irimie F.-D.
Journal of Pharmaceutical and Biomedical Analysis (2002) 28(2): 385-389
DOI: 10.1016/S0731-7085(01)00626-4 -
Synthesis of optically active 3-substituted-10-alkyl-10H-phenothiazine-5-oxides by enantioselective biotransformations
Toşa M., Paizs C., Majdik C., Novák L., Kolonits P., Irimie F.-D., Poppe L.
Tetrahedron Asymmetry (2002) 13(2): 211-221
DOI: 10.1016/S0957-4166(02)00077-0 -
Bioorganic synthesis of some (5-benzothiazol-2-yl-furan-2-yl)-methanols in cell catalysis using Saccharomyces cerevisiae
Irimie F.-D., Paizs C., Majdik C., Toşa M., Mişca R., Silaghi-Dumitrescu R.
Heterocyclic Communications (2002) 8(5): 489-492
DOI: 10.1515/HC.2002.8.5.489 -
Chemo-enzymatic preparation of hydroxymethyl ketones
Paizs C., Toşa M., Majdik C., Bódai V., Novák L., Irimie F.-D., Poppe L.
Journal of the Chemical Society. Perkin Transactions 1 (2002) 21: 2400-2402
DOI: 10.1039/b206851f -
Selective oxidaton methods for preparation of N-alkylphenothiazine sulfoxides and sulfones
Toşa M., Paizs C., Majdik C., Poppe L., Kolonits P., Silberg I.A., Novák L., Irimie F.-D.
Heterocyclic Communications (2001) 7(3): 277-282
DOI: 10.1515/HC.2001.7.3.277 -
Bioreduction with bakers' yeast of π - Deficient heterocyclic aldehydes
Irimie F.D., Afloroaei C., Toşa M., Paizs C.
Heterocyclic Communications (1999) 5(3): 253-256
DOI: 10.1515/HC.1999.5.3.253 -
ESR study of the dynamics of adsorbed nitroxide radicals on porous surfaces in the dehydration process
Damian G., Cozar O., Miclăus V., Paizs Cs., Znamirovschi V., Chis V., David L.
Colloids and Surfaces A: Physicochemical and Engineering Aspects (1998) 137(1-3): 1-6
DOI: 10.1016/S0927-7757(97)00092-7 -
Bakers' yeast-mediated reductions of some nitro-dibenzofurans
Irimie F.-D., Paizs C., Toşa M.-I., Afloroaei C., Miclăuş V.
Heterocyclic Communications (1997) 3(6): 549-553
DOI: 10.1515/HC.1997.3.6.549 -
Oxidarea metanolului la formaldehidă pe catalizatori oxidici de Mo-Fe I. Modelul matematic de bilanţ de masă
Toşa C., Miclăuş V., Toşa M., Pop A., Paizs C.
Revista de Chimie (1997) 48(4): 284-290 -
Oxidarea metanolului la formaldehidă pe catalizatori oxidici de Mo-Fe II. Modelarea matematică şi analiza procesului
Pop A., Paizs C., Toşa C., Toşa M., Miclăuš V.
Revista de Chimie (1997) 48(7): 616-620