|
The aim of our project is to develop new, innovative immobilized lipase
and ketoreductase enzyme systems with excellent
enantiomer selectivity and appropriate yields from microorganisms. Our products
will significantly decrease the production costs of newly developed enantiopure building blocks due to the achievable high
enantiomer selectivity (E) values
and yields.
Objectives: 1. Enzymes isolation from a
large number of available microorganisms 2. Screening
for lipase activity 3. Purified
enzyme product and identification of sequences
of the most promising enzyme candidates 4. Enzyme
and cell immobilization 5.
Optimized enzyme production applying the selected strains in lab-scale 6.
Optimized enzyme production applying the selected strains in 10 litre-scale. |
|
|
|
|
