MIO-ENZYME KIT WITH DEFINED AND EXTENDED SUBSTRATE DOMAIN

Scientific reports and results

Scientific reports:


Published papers:

  1. A novel phenylalanine ammonia-lyase from kangiella koreensis

    Varga A., Bata Z., Csuka P., Bordea D.M., Vértessy B.G., Marcovici A., Irimie F.D., Poppe L., Bencze L.C.
    Studia Universitatis Babes-Bolyai Chemia (2017) (): accepted

  2. Covalently immobilized lipases are efficient stereoselective catalysts for the kinetic resolution of rac-(5-Phenylfuran-2-yl)-β-alanine ethyl ester hydrochlorides

    Nagy B., Galla Z., Bencze L.C., Toșa M.I., Paizs C., Forró E., Fülöp F.
    European Journal of Organic Chemistry (2017) 2017(20): 2878-2882
    DOI: 10.1002/ejoc.201700174

  3. Expanding the substrate scope of phenylalanine ammonia-lyase from: Petroselinum crispum towards styrylalanines

    Bencze L.C., Filip A., Bánóczi G., Toşa M.I., Irimie F.D., Gellért Á., Poppe L., Paizs C.
    Organic and Biomolecular Chemistry (2017) 15(17): 3717-3727
    DOI: 10.1039/c7ob00562h

  4. Aminated single-walled carbon nanotubes as carrier for covalent immobilization of phenylalanine ammonia-lyase

    Bartha-Vári J.H., Bencze L.C., Bell E., Poppe L., Katona G., Irimie F.-D., Paizs C., Toşa M.I.
    Periodica Polytechnica Chemical Engineering (2017) 61(1): 59-66
    DOI: 10.3311/PPch.10417

  5. Expression and purification of recombinant phenylalanine ammonia-lyase from Petroselinum crispum

    Dima N.A., Filip A., Bencze L.C., Oláh M., Sátorhelyi P., Vértessy B.G., Poppe L., Paizs C.
    Studia Universitatis Babes-Bolyai Chemia (2016) 61(2): 21-34

  6. MIO-enzyme toolbox: cloning, expression and purification of recombinant RtPAL

    Filip A., Bencze L.C., Paizs C., Poppe L., Irimie F.D.
    Studia Universitatis Babes-Bolyai Biologia (2015) 61(Sp. Iss.): 39-43

Conference publications:

  1. Bencze L.C., Filip A., Nagy E.Zs.A., Nagy B., Banoczi G., Poppe L., Paizs C.
    Rational design of phenylalanine ammonia lyase from Petroselinum crispum (PcPAL) towards sterically demanding phenylalanine analogues
    VII EFMC International Symposium on Advances in Synthetic and Medicinal Chemistry, Viena (Austria), 2017, Poster Section

  2. Bordea D. M., Varga A., Bencze L.C.
    Molecular Cloning, isolation and characterization of novel, highly active phenylalanine ammonia lyase from Pseudozyma antartica
    XIVth Edition of the International Conference “Students for Students”, Cluj-Napoca, 2017, Poster Section
    Award Certificate – for the best undergraduate poster at the Internal Conference Student for Student, 2017

  3. Tork S.D., Filip A, Nagy Z.
    Novel PcPAL mutants exhibiting broadened substrate scope Pseudozyma antartica
    XIVth Edition of the International Conference “Students for Students”, Cluj-Napoca, 2017, Oral presentation
    THE GO GREEN! APPROACH award granted by SPI (Special Pro Installations)

  4. Filip A., Bencze L.C., Paizs C., Poppe L., Irimie F.D.
    MIO-enzyme toolbox: cloning, expression and purification of recombinant RtPAL
    International Conference Molecular Biology - Current Aspects and Prospects (ICMB-CAP), Cluj-Napoca, 6-8 November, 2015
    WEB: conference webpage

  5. Filip A., Banoczi G., Poppe L., Paizs C., Irimie F.D., Bencze L.C.
    Expanding the substrate range of phenylalanine ammonia lyase from Petroselinum crispum towards styryl-alanines
    Biotransformations for Pharmaceutical and cosmetic industry, Varsovia, 2016
    Gold medal award- Poster Section

  6. Nagy E.Zs.A., Filip A., Bencze L.C., Paizs C., Irimie F.D.
    Expanding the substrate range of PcPAL towards biphenyl-alanines
    16th CEEPUS Symposium and Summer School on Bioanalysis, Varsovia, 2016

  7. Filip A, Tork D.S., Bencze L.C., Banoczi G., Irimie F.D., Poppe L., Paizs C.
    MIO-enzyme toolbox: F137V mutant of phenylalanine ammonia-lyase from Petroselinum crispum with improved substrate tolerance and stereoselectivity
    Action COST CM1303 SysBiocat Training School, Siena, 2016

  8. Bencze L.C., Filip A., Banoczi G., Tosa M.I., Irimie F.D., Poppe L., Paizs C.
    Styryl-alanines as novel substrates for phenylalanine ammonia lyases
    International Symposium on Synthesis and Catalysis (ISYSYCAT), Evora (Portugal), 2015
    Poster awarded with runner-up prize in the Catalysis section