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Stages |
First Step 2008
- Preparation and characterisation of mono- and bis-pyrazoles from the corresponding chalcones.
- Carbometallation and subsequent functionalisation of the pyrazolylphenothiazines.
- Spectroscopic characterisation and molecular modelling of the metallacycles and 3,4-disubstituted- and 3,4,6,7-tetrasubstituted phenothiazines.
Second Step 2009
- Preparation and characterisation of chiral bis-hydrazones of C2-symmetry.
- Carbometallation and subsequent functionalisation of the chiral bis-hydrazones associated with cross-coupling- and condensation reactions.
Spectroscopic characterisation and molecular modelling of the chiral products including ligands and metal complexes. |
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