Stages

First Step 2008

  1. Preparation and characterisation of mono- and bis-pyrazoles from the corresponding chalcones.
  2. Carbometallation and subsequent functionalisation of the pyrazolylphenothiazines.
  3. Spectroscopic characterisation and molecular modelling of the metallacycles and 3,4-disubstituted- and 3,4,6,7-tetrasubstituted phenothiazines.

Second Step 2009

  1. Preparation and characterisation of chiral bis-hydrazones of C2-symmetry.
  2. Carbometallation and subsequent functionalisation of the chiral bis-hydrazones associated with cross-coupling- and condensation reactions.
Spectroscopic characterisation and molecular modelling of the chiral products including ligands and metal complexes.