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Web of knowledge for DONTAS Contract number 171 National Authority: UEFISCDI |
UNIVERSITATEA BABES BOLYAI FACULTATEA DE CHIMIE SI INGINERIE CHIMICA
Development of new tools and smart Composites based on advanced nanotehnology FOR medical applications
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· Project objectives
Main objectives: ♦¨development of new tools and smart composites based on advanced nanotechnology for medical applications ♦¨development and optimization of new nanofabrication strategies for biomaterials as thin films, with polyfunctional properties, obtained by specific methods of molecular or colloidal self assembly ♦¨development and optimization of new nanofabrication methods for polyfunctional supramolecular systems in aqueous solutions and at the air/water interface using polymer films ♦¨development of improved surgical methods and technics using DONTAS innovative materials and smart composites ♦¨development of novel metallic implants ♦¨realization and characterization of multifunctional nanostructures made from nano hydroxyl phosphates, pure or modified with different cations or anions, as well as from nano silicates, embedded in polymeric matrices (collagen: COL, chitosan: CHI, poly methyl methacrylate: PMMA, or poly-Bis-GMA), applicable in nanobiotechnology and nanomedicine.
Specific objectives: ♦Novel fabrication strategies for nanoparticles (NPs) of nano hydroxyl phosphates, pure or modified with Si, Mg, Zn, for medical use, as bone substitutes and in scaffolds for cell cultures ♦Investigation of molecular and colloidal self association/organization in aqueous solutions ♦Characterization of inorganic NPs of nano hydroxyl phosphates, pure or modified with different cations or anions by spectroscopy (FTIR), calorimetry (DSC, DTA, TG), X rays diffraction (XRD), BET surface area analysis, electron microscopy (SEM, TEM), atomic force microscopy (AFM). ♦Realization and characterization of mixed systems (e.g. thin films or bone cements) made from nano hydroxyl phosphates, pure or modified with various cations, or from nano silicates, in presence of polymers ♦Large scale dissemination: articles (8), communications (8), patent application (1); ♦ PhD (3), and graduation theses.
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