SELF-NAVIGATED INTEGRIN RECEPTORS SEEKING “THERMALLY-SMART” MULTIFUNCTIONAL FEW-LAYER GRAPHENE-ENCAPSULATED MAGNETIC NANOPARTICLES FOR MOLECULAR MRI-GUIDED ANTICANCER TREATMENTS IN “REAL TIME” PERSONALIZED NANOMEDICINE

EuroNanoMed-II, PN III, ERA-NET code ID_57, nr. 8/2015

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1. WP1. – Molecular modeling and proof of concept
• Task1.2. Optimalization of polymeric nanogel size to immobilize the enzyme
• Task1.2.a Modelling of the enzyme
• Task1.2.b Polymer size and shape
• Task1.3. Modeling of enzyme-polymeric nanogel-GEMNS interactions as a function oftemperature
2. WP4. – Cellular, molecular and nanosafety in vitro/in silico studies
• Task4.5. Prediction of theranostic GEMNS toxicities using QSAR strategies (in silico)
• Task 4.5a. QSPR studies
• Task 4.5b. QSAR studies