Scientific papers
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Phenylalanine ammonia-lyases: combining protein engineering and natural diversity
Tomoiagă R.B., Tork S.D., Filip A., Nagy L.C., Bencze L.C.
Applied Microbiology and Biotechnology (2023) 107(4): 1243-1256
DOI: 10.1007/s00253-023-12374-x -
Engineered, Scalable Production of Optically Pure l-Phenylalanines Using Phenylalanine Ammonia-Lyase from Arabidopsis thaliana
Tork S.D., Nagy E.Z.A., Tomoiagă R.B., Bencze L.C.
Journal of Organic Chemistry (2023) 88(2): 852-862
DOI: 10.1021/acs.joc.2c02106 -
Towards a general approach for tailoring the hydrophobic binding site of phenylalanine ammonia-lyases
Tork S.D., Moisă M.E., Cserepes L., Filip A., Nagy L.C., Irimie F.D., Bencze L.C.
Scientific Reports (2022) 12(1): 10606
DOI: 10.1038/s41598-022-14585-0 -
Saturation mutagenesis for phenylalanine ammonia lyases of enhanced catalytic properties
Tomoiagă R.B., Tork S.D., Horváth I., Filip A., Nagy L.C., Bencze L.C.
Biomolecules (2020) 10(6): 838
DOI: 10.3390/biom10060838 -
Mapping the Hydrophobic Substrate Binding Site of Phenylalanine Ammonia-Lyase from Petroselinum crispum
Nagy E.Z.A., Tork S.D., Lang P.A., Filip A., Irimie F.D., Poppe L., Toşa M.I., Schofield C.J., Brem J., Paizs C., Bencze L.C.
ACS Catalysis (2019) 9(9): 8825-8834
DOI: 10.1021/acscatal.9b02108 -
The production of L- and D-phenylalanines using engineered phenylalanine ammonia lyases from Petroselinum crispum
Tork S.D., Nagy E.Z.A., Cserepes L., Bordea D.M., Nagy B., Toşa M.I., Paizs C., Bencze L.C.
Scientific Reports (2019) 9(1): 20123
DOI: 10.1038/s41598-019-56554-0 -
Tailored Mutants of Phenylalanine Ammonia-Lyase from Petroselinum crispum for the Synthesis of Bulky l- and d-Arylalanines
Filip A., Nagy E.Z.A., Tork S.D., Bánóczi G., Toşa M.I., Irimie F.D., Poppe L., Paizs C., Bencze L.C.
ChemCatChem (2018) 10(12): 2627-2633
DOI: 10.1002/cctc.201800258