Contract: 91TE/03.01.2025
Design of organotin(IV) chalcogenide clusters as building blocks for metal organometallic networks
Design of organotin(IV) chalcogenide clusters as building blocks for metal organometallic networks
Project timespan
2025 -- 2026
2025 -- 2026
Abstract
The aim of the current project proposal is the development of a new generation of organotin(IV) chalcogenide clusters with the general formula [(RSn)4E6] E = S, Se, Te, decorated with functional aryl fragments (i.e. R = -C6H4-CHO, -C6H4-COOH, -C6H4-CN, -C6H4-CH=NR’) and their usage as linkers for metal-organometallic networks (MOMNs). This includes the synthesis and structural characterization of the designed species; in addition, the optical properties, single-source precursor potential, and biological (cytotoxicity, antitumor, apoptosis, and autophagy assay) activity for selected compounds will also be studied. The following objectives (O) will be developed:
O1. Access to aryltin(IV) di- and trichlorides decorated with ortho-functionalized organic fragments.
O2. Access to aryltin(IV) di- and trichlorides decorated with para-functionalized organic fragments.
O3. Design and synthesis of organotin(IV) chalcogenides clusters.
O4. Investigation of the coordination abilities of the organotin(IV) chalcogenides clusters.
O5. Structural investigation of the isolated compounds.
O6. Studies on the cytotoxicity and optical properties of the organotin(IV) species.
The novelty elements include the evaluation of the unexplored coordination potential for the functionalized organotin(IV) clusters to generate MOMNs and the investigation of the cooperative effect between Sn and different chalcogenides in terms of biological activity, catalytic and optical properties.
The aim of the current project proposal is the development of a new generation of organotin(IV) chalcogenide clusters with the general formula [(RSn)4E6] E = S, Se, Te, decorated with functional aryl fragments (i.e. R = -C6H4-CHO, -C6H4-COOH, -C6H4-CN, -C6H4-CH=NR’) and their usage as linkers for metal-organometallic networks (MOMNs). This includes the synthesis and structural characterization of the designed species; in addition, the optical properties, single-source precursor potential, and biological (cytotoxicity, antitumor, apoptosis, and autophagy assay) activity for selected compounds will also be studied. The following objectives (O) will be developed:
O1. Access to aryltin(IV) di- and trichlorides decorated with ortho-functionalized organic fragments.
O2. Access to aryltin(IV) di- and trichlorides decorated with para-functionalized organic fragments.
O3. Design and synthesis of organotin(IV) chalcogenides clusters.
O4. Investigation of the coordination abilities of the organotin(IV) chalcogenides clusters.
O5. Structural investigation of the isolated compounds.
O6. Studies on the cytotoxicity and optical properties of the organotin(IV) species.
The novelty elements include the evaluation of the unexplored coordination potential for the functionalized organotin(IV) clusters to generate MOMNs and the investigation of the cooperative effect between Sn and different chalcogenides in terms of biological activity, catalytic and optical properties.
Budget
| Budget chapter (expenses) | 2025 (lei) | 2026 (lei) | Total | |
|---|---|---|---|---|
| 1 | Salaries | 163,200 | 163,200 | 326,400 |
| 2 | Inventory | 50,000 | 24,850 | 74,850 |
| 3 | Mobility | 8,000 | 12,000 | 20,000 |
| 4 | Overhead | 41,240 | 37,510 | 78,750 |
| 5 | Total | 262,440 | 237,560 | 500,000 |
Results
For information about unpublished results contact Lect. Dr. Adrian-A. Someșan at adrian.somesan@ubbcluj.ro.
For information about unpublished results contact Lect. Dr. Adrian-A. Someșan at adrian.somesan@ubbcluj.ro.