Home

Abstract

Objectives

Stages

Research team

Results

2012

2013

2014

2015

WP1. The stereoselective synthesis of optically pure unnatural a-arylalanines mediated by immobilized PAL

WP2. The stereoselective synthesis of optically pure unnatural a-arylalanines mediated by immobilized cells

 

Scientific report on Stage IV (rom); Scientific report on Stage IV (eng)

 

Scientific article:

 

1. Judith H. Bartha-Vári, Monica I. Toşa, Florin-Dan Irimie, Diána Weiser, Zoltán Boros, Beáta G. Vértessy], Csaba Paizs,László Poppe: Immobilization of phenylalanine ammonia-lyase on single-walled carbon nanotubes for stereoselective biotransformations in batch and in continuous-flow modes, , ChemCatChem 2015, 7(7), 1122-1128; DOI: 10.1002/cctc.201402894R1 (Abstract)

2. Ferenc Ender, Diána Weiser, Botond Nagy, Csaba László Bencze, Csaba Paizs, Péter Pálovics, László Poppe: Microfluidic multiple cell chip reactor filled with enzyme-coated magnetic nanoparticles An efficient and flexible novel tool for enzyme catalyzed biotransformations, Journal of Flow Chemistry, submitted, 2015 (Abstract)

3. Diana Weiser, Laszlo Csaba Bencze, Gergely Banoczi, Ferenc Ender, Robert Kiss,Eszter Kokai, Andras Szilagyi, Beata G. Vertessy, Oeden Farkas, Csaba Paizs, Laszlo Poppe: Phenylalanine Ammonia-Lyase-Catalyzed Deamination of an Acyclic Amino Acid: Enzyme Mechanistic Studies Aided by a Novel Microreactor Filled with Magnetic Nanoparticles, ChemBioChem 2015, 16, 2283 – 2288 (Abstract)

 

Conferences

1.   László Csaba Bencze, Alina Filip, Gergely Bánóczy, Monica Ioana Toşa, Florin Dan Irimie, László Poppe, Csaba Paizs: Styryl-alanines as novel substrates for phenylalanine ammonia lyase, IsySyCat (International Symposium on Synthesis and Catalysis), Evora, 2-4 September 2015, Portugal (Poster) Abstract

2.   Poppe, L.; Weiser, D.; Ender, F.; Bartha-Vári, H.; Paizs, C.; Vértessy, B. G.: Nanosupported phenylalanine ammonia-lyase in microreactors. 3rd International Conference Implementation of Microreactor Technology in Biotechnology IMTB 2015; 10-13 May 2015 Opatija, Croatia

3.   Boros, Z.; Weiser, D.; Ender, F.; Bartha-Vári, H.; Oláh, M.;, Falus, P.;Paizs, C.; Vértessy, B.G.; Servi, S.; Poppe, L.: Immobilized enzymes in microfluidic systems phenylalanine ammonia-lyase-, lipase- and protease-catalyzed processes. Biotrans 2015, 12th International Symposium on Biocatalysis. 26-30 July, 2015, Vienna, Austria

4.   Varga, A; Nagy, B.; Miklos, M.; Irimie, FD.; Poppe, L.; Paizs, C.: Stereoselectivity of PAL under non-optimal conditions, 29th Annual Symposium of the Protein-Society, JUL 22-25, 2015, Barcelona, SPAIN

5.   Filip, A.; Bartha-Vari, JH.; Banoczy, G.; Poppe, L.; Paizs, Cs.; Irimie, FD: Non-natural aminoacids via the MIO-enzyme toolkit, 29th Annual Symposium of the Protein-Society, JUL 22-25, 2015, Barcelona, SPAIN

 

2016